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Genetic evidence has highlighted that overexpression or knock out of the Gpx4 gene resulted in reduction or induction of ferroptosis, respectively [1, 18]

243,244,245,246 For example, the KD supplemented with medium-chain TG enhanced the antitumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model

Media and culture conditions Wild-type yeast strains were pre-cultured in 5 mL of YP20D medium containing 10 g/L yeast extract, 20 g/L Bacto Peptone, and 20 g/L glucose at 30 C and 250 rpm for 48 h