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C5aR1 inhibition was achieved treating animals with DF3966A (30 mg/kg, os) or with Avacopan (30 mg/kg, os) administered respectively 3 and 1 h before paclitaxel administration, according to their pharmacokinetic profile (Supplementary information paragraphs 7 and 8 and [29])

GLP-1 agonists slow gastric emptying and reduce thirst signalling, which can lead to mild chronic dehydration in patients who don't consciously increase fluid intake

The first draft, prepared by consultants or, more usually, staff from an IPCS Participating Institution, is based initially on data provided from the International Register of Potentially Toxic Chemicals, and reference data bases such as Medline and Toxline

Cardiovascular disease: mitochondrial dynamics and mitophagy crosstalk mechanisms with novel programmed cell death and macrophage polarisation

Pim Family Kinases Enhance Tumor Growth of Prostate Cancer Cells