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Liang X., Weng J., You Z., et al., Oxidative Stress in Cancer: From Tumor and Microenvironment Remodeling to Therapeutic Frontiers, Molecular Cancer 24, no

Document dosing rationales (route, concentration, frequency) and use pilot results to set dose escalation or fixeddose arms in the main study

These findings suggest that grape seed PCs can substantially reduce oxidative stress resulting from UVB exposure while providing protective effects against skin damage caused by UVB radiation (58)