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For home monitoring, standardized questionnaires such as the Michigan Neuropathy Screening Instrument (MNSI) and the Neuropathy Total Symptom Score (NTSS-6) provide structured self-assessment tools

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Multiplex immunofluorescence (mIF) and image analysis Sections from FFPE processed explants were stained using Opal 4-Color Manual IHC Kit (Cat# NEL810001KT, Akoya Biosciences, Boston, MA, USA) according to manufacturers instructions

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Nonetheless, their long-term systemic impact and frequent use alongside or after chemotherapy justify their inclusion in comprehensive toxicity evaluations

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