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The gut microbiota can influence the composition of lipids in the hosts serum, adipose tissue, and liver, particularly triglycerides and phosphatidylcholine, thereby impacting the hosts energy and lipid metabolism [54]

In addition, age or disease (e.g., heart failure)-related alterations in the gut-blood barrier (i.e., leaky gut) resulted in increased plasma TMA levels in rats (Jaworska et al., 2019

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