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Asian Pac J Allergy Immunol 25(1):1725 Shen YL, Jin X, Chen W et al (2020) Interleukin-22 ameliorated acetaminophen-induced kidney injury by inhibiting mitochondrial dysfunction and inflammatory responses

They migrate more efficiently toward damaged areas and begin synthesizing new collagen matrix upon arrival

The structural modifications that extend its half-life also mean it accumulates in the body over time, which is why dose escalation protocols start low and increase gradually

2020;4(Suppl 2):1452

Also, due to clinical contraction and spared use of the injured leg, muscle fiber atrophy occurred (Figure 13)
