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The strength and extent of DNA damage determines the cell fate, that is, activation of DNA repair and subsequent cell survival or elimination of the severely damaged cells through programmed cell death
Chen, TianfengJournal of Materials Chemistry B: Materials for Biology and Medicine (2018), 6 (4), 568-579CODEN: JMCBDV

Elevated NAD+ promotes mitochondrial biogenesis and function, improving cellular energy metabolism through enhanced oxidative phosphorylation

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