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Am J Physiol Gastrointest Liver Physiol 290:G30-35

10.1158/1078-0432.ccr-09-0737 24 ChehelgerdiM.ChehelgerdiM
By preserving NAD+ and SAM in both fat and muscle tissue, NNMT inhibition may theoretically address the metabolic dysfunction underlying both excessive fat storage and impaired muscle maintenance

They are supposed to help with antioxidant response and repair

Interplay between the NADP-linked thioredoxin and glutathione systems in Arabidopsis auxin signaling