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On the other hand, a restriction in lactose intake is suggested in hypothyroid patients in need for levothyroxine treatment affected by lactose malabsorption, a condition with a global prevalence of 68%, due to the non-persistence of the expression of lactase gene [154]

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(In Japanese) [Google Scholar] 871.Matsuyama A., Takahashi J., Itakura H

That said, dosages up to 1,200 mg/day have been studied with no serious adverse effects reported. After taking two capsules, he reported no noticeable side effects and gave the supplement another 5 for this
