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Clinical studies have shown that many patients with autoimmune diseases such as RA, multiple sclerosis, and ankylosing spondylitis are accompanied by increased intestinal permeability (Ciccia et al., 2017

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[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Carr R.S., Neff J.M

Within these populations are people with risk factors that might make them better candidates than others, such as: Stress: Chronic stress not only promotes an inflammatory state but also can prolong bacterial infections and discourage wound closure.7 21 22 Overweight or obesity: People with excess weight are also at risk for chronic inflammation, persistent infections, and slower wound healing