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However, the supplying of IID through co-expression fails to rescue the formation of an intact polymerase complex due to its relatively low binding affinity for MARL (Supplementary Fig

Continue increasing by 0.25 to 0.5 mg every 4 weeks until reaching the target dose or maximum tolerated dose

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Model: Female US NIH National Institute on Aging (NIA) Aged Rodent Colony mice aged 22 months Dosage: 10 mg/kg of 5-amino-1MQ administered with subcutaneous injections for eight weeks

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