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Therefore, combined drug therapy strategies have been widely explored to enhance the effects of stem cell therapy

NRF2 Pathway: Mechanisms and Functions NRF2 is a transcription factor that belongs to the cap 'n' collar (CnC) family and contains a basic-region leucine zipper (bZIP) domain

showed that transduction of Hnf1 and Foxa3 directly induced MEFs into hepatic stem cells which had the bipotential of differentiating into hepatocytes and cholangiocytes (Yu et al., 2013)

Metabolism and Energy Glutathione plays a role in enzyme function and cellular energy production, making it useful in combating fatigue and promoting metabolic balance

Ethics declarations Competing interests Dr NL reports Stock and Other Ownership Interests at Senseonics, AbbVie, Verrica, and research funding from Omeros, all outside the submitted work