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The review found that selenium supplementation - which works primarily by supporting glutathione peroxidase (GPx) activity - produced: *Significant reduction in TPOAb levels (SMD 0.96
Studies suggest subcutaneous administration achieves 7085% bioavailability compared to oral routes, though oral protocols at 100150mg compensate for first-pass metabolism
PMID: 209 WastykHCFragiadakisGKPerelmanDDahanDMerrillBDYuFBet al
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