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Complications Complications of Peyronies disease may include: Inability to have sexual intercourse Difficulty achieving or maintaining an erection (erectile dysfunction) Anxiety or stress about sexual abilities or the appearance of your penis Stress on your relationship with your sexual partner Difficulty fathering a child, because intercourse is difficult or impossible Reduced penis length Penile pain Patient evaluation Diagnosis of Peyronies disease is readily made by a typical history and penile examination

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