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Kyosuke Uno and Koichi Kawada were involved in the analysis and interpretation of the data and critical review of the paper

6,7 Blood tests may be helpful in determining if a clot exists and for monitoring the bloods propensity to form clots

For 200 mg vials, use 2 mL of bacteriostatic water to achieve a concentration of 100 mg/mL

doi: 10.3389/fphar.2026.1774791 Received 24 December 2025 Revised 22 February 2026 Accepted 25 February 2026 Published 27 March 2026 Volume 17 - 2026 Edited by Ismail Laher, University of British Columbia, Canada Reviewed by Meganathan Kannan, Central University of Tamil Nadu, India Paresh Kulkarni, Cleveland Clinic, United States Updates Copyright 2026 Yadava, Dontiboina, Dugluri, Yadagiri, Choudhury and Kakarla

Xiao-Liang Zhang, [email protected] These authors have contributed equally to this work ORCID: Ya-Ping Fang, orcid.org/0000-0002-7996-1001