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[DOI] [PubMed] [Google Scholar] 198.Kumar M.R., Yeap S.K., Mohamad N.E., Abdullah J.O., Masarudin M.J., Khalid M., Leow A.T.C., Alitheen N.B

The enzyme is membrane-bound with its active site facing the external side of the cell

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[DOI] [PMC free article] [PubMed] [Google Scholar] [58].R.d.-b.c

The first evidence showing APP overexpression in DS was demonstrated within enlarged endosomes and lysosomes, where APP accumulation could be initiated at the fetal stage, as early as 28 wk of gestation (465)
