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104 patients were identified, 43 in the chemotherapy group and 61 in the non-chemotherapy group

As the first-line resident cells in the defense against myelin debris accumulation, activated microglia release C1q, which stimulates a neurotoxic phenotype in astrocytes and leads to the death of both neurons and OL cells 70

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[DOI] [PMC free article] [PubMed] [Google Scholar] Keller M, Mazuch J, Abraham U, Eom GD, Herzog ED, Volk HD, Kramer A, Maier B