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10.1038/onc.2012.67 52 YangY.YouX.QuanY.LuoS.LiL.ZengJ.et al
Thus, there is little data from which to draw conclusions about its safety, especially regarding long-term use in humans [2]
Lignin peroxidase (LiP), an extracellular enzyme purified from the white-rot fungus Phanerochaete chrysosporium , has been shown to effectively degrade and decolorize melanin in vitro through an oxidative process [190, 191]
The standard dose of 2,330 mcg per day (10 units from a 70 mg vial in 3 mL) assumes a 60 to 85 kg adult
