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Despite numerous studies reporting TMAO-induced endothelial dysfunction, the effects of TMAO on endothelial cell viability remain inconsistent
As opined above, this -helix structure dipole moment could stabilize the sulfuranyl free radical long enough to allow the radical to abstract labile allylic H-atoms from allylic C-atoms of acyl chains of phospholipids, thereby initiating the chain reaction of lipid peroxidation
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