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Apoptosis: a comprehensive overview of signaling pathways, morphological changes, and physiological significance and therapeutic implications

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This observation implies that hypoxia may potentially participate in DM pathogenesis by regulating HIF-1, stimulating RIG-I expression, and cooperating with other inflammatory factors

It is worth noting that hesperidin and its aglycone metabolite hesperetin demonstrated antiviral effects at multiple stages of COVID-19 infection

IKK potentials have been paid more and more attentions in the prevention and treatment of various diseases as the discovery of the first IKK inhibitor SPC839 ( 57 ) in 2001, therefore, its development has become a hot topic