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In this regard, systematic reviews suggest that oral collagen can contribute to reducing or delaying skin aging [82,83,84] and expanding its applications to meet the evolving dermatological challenges [85]

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Scand J Immunol 1981

HIF-1 and mechanisms of hypoxia sensing
Oxidative stress was induced by treatment with 400 M H 2 O 2 in the presence of the test product (3.2, 16, 80 M) or L-Ascorbic acid (100 M), followed by 24 h of incubation