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Currently, there are mainly three enzymes that catalyze endogenous H 2 S production, namely, cystathionine gamma-lyase (CSE), 3-mercaptopyruvate sulfurtransferase (3-MST), and cystathionine-beta-synthase (CBS) (Shackelford et al., 2021a)

Microglial NF-B activation under GSH-depleted conditions creates a pro-inflammatory loop where increased ROS promotes NF-B activation, which upregulates inflammatory cytokines and further stimulates oxidative stress (Liu et al., 2017

Severe anemia with hemoglobin below 8 may justify transfusion or hospitalization

94 Moreover, among age-related diseases, MPO levels are also elevated in elderly subjects with AD, showing that MPO might be an important molecular link between atherosclerosis and AD and probably a promising biomarker for the detection and risk stratification of AD patients

Targeting cytokine dysregulation in psoriasis: the role of dietary interventions in modulating the immune response