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[PMC free article: PMC3141088] [PubMed: 21527746] 684

Cincione IR, Graziadio C, Marino F, Vetrani C, Losavio F, Savastano S, Colao A, Laudisio D

Several DNA repair enzymes are iron dependent [54]

thus, the inhibition of pyruvate via gliotoxin can induce apoptosis in the human gloma cell line U87, synergize with temozolomide
