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Enzymatic detoxification: by providing essential coenzymes

10.1021/acssynbio.4c00161 79 WenJ.HuangS.HuQ.HeW.WeiZ.WangL.et al (2024)

Note, hepatic artery perfusion could be essential for recovery from hepatic venous outflow obstruction in rats, pointed out when usually occurring after 70% hepatectomy and right median hepatic vein ligation, in which the role of hepatic artery inflow is of particular importance, in the condition likely even more severe than the obstruction of the hepatic veins by ligation of the upper part of inferior caval vein[51]

Most of these genes are not involved in classic GH/IGF-I pathways

However, long-term injectable use has not been extensively studied in clinical trials