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Further studies are needed to provide more convincing evidence demonstrating the pathogenic role of HHcy in the progression of PD in animal and clinical studies

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Research shows Dihexa increases dendritic spine density by 40-50% in hippocampal neurons, with these new spines demonstrating functional characteristics of mature synapses including colocalization with presynaptic markers synapsin and VGLUT1, and generation of enhanced excitatory postsynaptic currents