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In ruminants, EOs exert significant effects on physiology primarily through their antimicrobial properties, which selectively modulate the rumen microbial ecosystem [96]

In flies, genetic suppression of two out of three AHCY homologs, systemically or in a tissue-specific manner, reduces age-related SAH accumulation and leads to lifespan extension [80]

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Furthermore, significant accumulation of TZ in the brain following administration indicates its ability to cross the bloodbrain barrier, highlighting its considerable promise for PD treatment [183]