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mTORC1 also phosphorylates TFEB (Martina et al., 2012), a master transcription factor coordinating lysosomal biogenesis and autophagic gene expression

dye-free or liquid versions of approved drugs)

These methods reveal that astrocyte Ca 2+ elevations, triggered by mechanical or electrical stimuli, drive glutamate release to modulate neuronal activity via ionotropic (iGluR) or metabotropic (mGluR) receptors, as seen in hippocampal slices where astrocyte Ca 2+ waves inhibit or enhance presynaptic neurotransmission, highlighting context-dependent metabolic coupling in physiological and stress conditions (Chen et al., 2023)

Mitochondrial Dysfunction in Aged Macrophages and Lung during Primary Streptococcus Pneumoniae Infection Is Improved with Pirfenidone

The present study aimed to investigate the protective effects of metformin and coenzyme CoQ10 individually and in combination against DOX-induced cardiotoxicity in male Wistar rats