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Subsequent research on murine model revealed that A1AT can inhibit both macrophages metalloproteinase (MMP-12) production and the release of TNF-alpha from alveolar macrophages, thereby reducing smoke-induced inflammation and the influx of inflammatory cells (23)
Diabetes 2006;55:27472756
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[DOI] [PubMed] [Google Scholar] 405.Lai Y, et al
Protein disulfides are also reduced by glutaredoxin (Grx), requiring GSH as a cofactor
