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Description

Glutathione has many important functions in our body, but most importantly, it is the king (or queen) of antioxidants, which essentially means that it protects cells (egg/sperm) from damage due to ROS such as lipid hydroperoxides (turning them into alcohols) and hydrogen peroxide (turning it into water)

The PPP is a shunt pathway split into two phases: oxidative and nonoxidative (Kamada et al., 2003)

The study authors note directly that this tissue accumulation is the source of long-term concern not acute poisoning, but the steady, dose-dependent loading of a neurotoxin into the brain, kidneys, liver, and other tissues over years of exposure

Wagenknecht LE, Scherzinger AL, Stamm ER, Hanley AJ, Norris JM, Chen YD, Bryer-Ash M, Haffner SM, Rotter JI (2009) Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort