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Additionally, oral supplements require daily adherence to maintain consistent levels, which can be a challenge for some people

doi: 10.1021/bi2007614

A Review on Prevalence and Causes of Peripheral Neuropathy and Treatment of Different Etiologic Subgroups with Neurotropic B Vitamins

Early in the morning, before you have any food and before you reach for your early bird pick-me-up cup of coffee seems to work for many people, but any time in the day (as long as you stay consistent!) should get the job done