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Several potential therapeutic targets related to cholesterol ester metabolism have been identified, including: Acyl-CoA:Cholesterol Acyltransferase (ACAT) : Inhibitors of ACAT, such as avasimibe and pactimibe, reduce cholesterol ester synthesis and intracellular lipid accumulation, offering potential benefits for reducing atherosclerosis progression and improving lipid profiles

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Deng X, Dong Q, Bridges D, Raghow R, Park EA, Elam MB (2015) Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase

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