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Description
Given that it is likely that a large proportion of children with ASD have abnormal mitochondrial function, it is possible that many of the comorbid GI abnormalities associated with ASD could be related, at least in part, to mitochondrial dysfunction
The LDL-derived cholesterol was found to be a negative regulator of HMG CoA reductase by decreasing its gene transcription and promoting its degradation (104)

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