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In clinical trials it produced some of the largest weight-loss and glycemic results of any incretin therapy, with a long half-life that supports a single weekly subcutaneous injection and a stepwise titration that keeps gastrointestinal effects manageable
10.1016/j.biomaterials.2021.120714 15 CostaM

Nonetheless, targeting this population is anticipated to provide new treatment opportunities
Pimpin, L

In cases of SLC31A1 deficiency [46], copper uptake can also occur through CTR2, which is encoded by SLC31A2 , as a compensatory mechanism [47]