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Hypothalamus is a key site for the regulation of energy homeostasis

doi: 10.1124/mol.106.033167

A coffee enema is an alternative colon cleanse where a coffee and water mixture is introduced into the colon to help detoxify the body, remove impurities, and support digestive health

The glucose-fatty acid cycle was first proposed by Philip Randle and co-workers in 1963 and is, therefore, sometimes referred to as the Randle cycle or Randle hypothesis