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Reference for stages of Vitamin B12 deficiency ( 3 ) Summary Numbness and tingling in the hands , legs, or feet is a common symptom

This disorder is characterized by progressive cerebellar ataxia beginning after puberty, by juvenile cataracts, and by tendinous or tuberous xanthomas

Zuccato C, Cattaneo E (2014) Huntingtons disease

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Whether these effects are due to HO-1 expression in SMC per se or due its expression in neighboring cells is not clear