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According to the fully adjusted model, after the highest tertile was compared with the lowest tertile, the plasma TMAO concentration (OR = 202 (95 % CI 104, 392)

doi: 10.3892/ijmm.2020.4711 517 CuiLWeiyaoJChenghongSLimeiLXinghuaZBoYet al

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Potential mechanisms range from changes in the extracellular matrix (myocardial fibrosis, inflammation) 79 to impaired calcium handling 80 or modification of sarcomeric proteins, 81 which have all been reviewed by others
