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Can vitamin B12 reduce melanin

Author Contributions Conceptualization, L.S., A.A.M., H.S

There is evidence for immune system dysfunction in FM, with altered levels of cytokines/chemokines and growth factors and other inflammatory biomarkers in the brain and spinal fluid indicating neuroinflammation may play a potential role [100,101]

Articular cartilage is composed of abundant proteoglycans in which sulfated glycosaminoglycan chains such as chondroitin sulfates are bound to a core protein such as aggrecan

Humane endpoints: Animals were euthanized if tumor volume exceeded 2000 mm, if tumors reached 10% of body weight, if body weight loss exceeded 2025%, or if signs of cachexia or severe distress were observed