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10.2174/1567201815666180926121104 93 KawakamiI.YoshinoH.FukumotoW.TamaiM.OkamuraS.OsakoY.et al (2022)

Furthermore, the suppression of HAP1 function in live neurons resulted in the inhibition of kinesin-dependent vesicular trafficking [71]

Targeting NAD(+) metabolism as interventions for mitochondrial disease
Tube formation was quantified as described previously (8)

This is the entire intellectual case for measurement-first longevity, and it is the principle behind the data-driven approach that figures like Eric Topol and Peter Attia have pushed into the mainstream, and that elite programs from Olympic sport science to NASA human-performance research have used for years: you do not guess, you instrument
