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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Laksmi M.H., Winaya K.K., Darmaputra I.G., Rusyati L.M., Indira I.G., Karmila I.G

To maintain the balance of ROS, the antioxidant system within organisms comprises endogenous enzymes (such as GPX and TrxR) and exogenous antioxidants (such as Vitamin E)

Thioredoxin 2 is a critical regulator of cytochrome c release and mitochondrial apoptosis

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Research into genetic variations in SOD genes also underscores their significance in CRC susceptibility and management, indicating that a deeper understanding of SODs roles may enhance therapeutic strategies [97]