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Scientific Classification A synthetic 16-amino-acid C-terminal peptide fragment derived from residues 177191 of a larger human polypeptide

Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

A LASSO regression was used to select a subset of the features with P values less than 0.05 as a minimal model, and McFaddens pseudo- R 2 was calculated

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7 Lyme arthritis is characterized by severe joint pain and swelling in the knee and other large joints