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GSH also conjugates electrophilic xenobiotics for elimination and has been linked to activation of the Nrf2/HO-1 cytoprotective pathway
Biomolecules 10 , 447 (2020)
In addition, DCA treatment alone caused ER stress to an extent that was nearly as robust as the bona fide ER stressor TM, as seen by splicing of Xbp1 (Figure 7F) and upregulation of UPR target genes (Figure 7G)
Body_ID: PB35012 Despite efficient chelation of metals, ROS are formed in the body and do cause chemical damage
Therefore, to test this theory, NAFLD mice were treated with PARP inhibitors or NR
