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Moreover, hyperinsulinemia, a phenomenon associated with insulin resistance, results in high levels of insulin and glucose in blood, leading to an increase in the release of proinflammatory cytokines, promoting microglial proliferation and proinflammatory polarization in vivo (Yang et al., 2022)

[Google Scholar] (49).Enders D

The calculated average suicide prevalence was 8.12 (range: 6.779.47) within the latitude range of 014, 8.54 (range: 2.9214.15) for 1529, 9.97 (range: 6.2913.65) across 3044, 19.23 (range: 16.6721.80) for 4559, and 15.28 (range: 9.1221.44) within 6075

Partaking in daily exercise at a moderate-intensity can improve brain glucose metabolism and provide neuroprotective benefits (Dougherty et al., 2017)

However, functional outcomes in schizophrenia are limited by the lack of effective pharmacological and psychosocial interventions for cognitive impairment