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However, electrophysiological studies combined with pharmacological application of GABA A receptor positive allosteric modulators have revealed that subunits, previously defined as synaptic are also found in somatic membranes of neurons (Lindquist and Birnir, 2006

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Such reduction-oxidation reactions are characterized by a free energy change that shares some conceptual features with that used to describe pKa in acid-base reactions where proton transfer is involved rather than electron transfer