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Chemical biotransformation of MC primarily takes place in the liver, in which chemically reactive and stable metabolites are formed via two processes, namely, oxidation by microsomal cytochrome P-450 and conjugation by GST

GSTM1 null individuals older than 4 years had more frequently graft versus host disease (P=0.03)

Antioxidants inhibit oxidation and help to prevent non-communicable diseases, such as aging and inflammatory processes, tumors, kidney and liver diseases, coronary heart disease, cataracts, renal toxicity, and neurological diseases

Conclusions Although serum carnitine concentration can appear deceptively normal, skeletal muscle carnitine stores can be reduced in patients with severe muscular atrophy

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