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Some neurological effects improve with sustained abstinence

In fact, one of the primary treatments for acetaminophen overdose is to give acetylcysteine, which is a precursor to glutathione

Strode C, Wondji CS, David J-P et al (2008) Genomic analysis of detoxification genes in the mosquito Aedes aegypti

The same authors also demonstrated that MPP+ induced ferroptosis in Lund human mesencephalic (LUHMES) cells, which are immortalized dopaminergic neuronal precursor cells that can differentiate into dopaminergic neurons (Zhang et al., 2014)

[PMID: 11028671 DOI: 10.1034/j.1399-3003.2000.016003534.x] [DOI] [PubMed] [Google Scholar] 53.Roum JH, Borok Z, McElvaney NG, Grimes GJ, Bokser AD, Buhl R, Crystal RG