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doi:10.1016/j.repbio.2019.07.005

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The following section covers the peptides with the most substantive research behind their antidepressant properties, presented in order of evidence strength and mechanistic interest

In the pool of placebo-controlled trials in adults, severe gastrointestinal adverse reactions occurred more frequently among patients receiving MOUNJARO (5 mg 1.3%, 10 mg 0.4%, 15 mg 1.2%) than placebo (0.9%)

BPC-157 is a synthetic string of 15 amino acids created by combining two different regions of a gastric protective protein, it does not occur in nature, nor does it have any natural function of its own