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SkQ1 and SkQR1 are designed from MitoQ and display greater permeability in membrane transportation than MitoQ (Jankauskas et al., 2012
N -acetylcysteine - a safe antidote for cysteine/glutathione deficiency

Regarding the GSH shuttle, despite its central role in antioxidant defense, clinical trials aiming to boost brain GSH levels through precursor supplementation have shown inconsistent outcomes

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