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Finally, activated Ceg14 is incapable of hydrolyzing ADP into AMP, which suggests that Ceg14 specifically targets ATP and hydrolyzes it into AMP and pyrophosphate (Fig
fatigue/tiredness appears in the broader tolerability profile but was not the dominant safety signal compared with GI events
10.1016/j.jacc.2020.11.010 191 RoyP.OrecchioniM.LeyK
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