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DNA methylation at regions of high CpG density, known as CpG islands and CpG island shores proximal to gene promoters and enhancers, silences gene expression while methylation in gene bodies is associated with active transcription [88, 89]
10.1136/bmjdrc-2021-002595 144 Jay WidmerR.LermanA
doi: 10.3233/jad-2008-15314
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The accessibility in the external part of the TM5 of the glutamate transporter EAAT1 is conformationally sensitive during the transport cycle
