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CS exposure is known to alter lipid metabolism by impairing PPAR signaling, leading to increased lipid accumulation in alveolar macrophages, which exacerbate chronic inflammation 65

9,10 Mitochondria, which are critical for cellular respiration and metabolism, suffer damage to their own mitochondrial DNA by the actions of reactive oxygen species and peroxynitrite compounds, and they have been directly implicated in the process leading to cessation of ATP synthesis

Treatment of AS mice with P-Mn/TI@mHSA The prophylactic and therapeutic efficacy of P-Mn/TI@mHSA against atherosclerotic plaques was evaluated

Bamagoos AA, Mallhi ZI, El-Esawi MA, Rizwan M, Ahmad A, Hussain A, Ali S (2022) Alleviating lead-induced phytotoxicity and enhancing the phytoremediation of castor bean ( Ricinus communis L.) by glutathione application: new insights into the mechanisms regulating antioxidants, gas exchange and lead uptake